Our research already showed the potential of using phages to counter recurrent root canals treatment failures which are caused by Enterococcus faecalis. We demonstrated how our isolated phages were not only able to eradicate the plaque the bacterium creates but also were able to prevent it from creating a root infection in an ex vivo model.

We are also one of the few teams in the world who were able to successfully isolate phages against Streptococcus mutans, a major pathogen responsible for the development of dental caries and tooth decay, the most common health condition in the last decade.

Our efforts are also focused on hunting phages against Poryrphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, keystone pathogens that can trigger periodontitis – a highly prevalent disease that is not only one of the leading causes of tooth loss but also has been linked with a variety of systemic diseases such as diabetes and Alzheimer’s.

We diligently work to expand our ever-growing library of anti-oral pathogen phages while researching their implementation and potential as an effective tool to combat many oral and dental diseases. We hope to pave the way for developing phage-based dental treatments and products to be a selective, safe and effective therapeutic strategy in dentistry.